Saluron, Adverse Reactions

Adverse Reactions

Saluron

The following adverse reactions have been observed, but there has not been enough systematic collection of data to support an estimate of their frequency.

Gastrointestinal system reactions: anorexia, gastric irritation, nausea, vomiting, cramping, diarrhea, constipation, jaundice (intrahepatic cholestatic jaundice), pancreatitis.

Central nervous system reactions: dizziness, vertigo, parathesias, headache, xanthopsia.

Hematologic reactions: leukopenia, agranulocytosis, thrombocytopenia, aplastic anemia.

Dermatologic-Hypersensitivity reactions: purpura, photosensitivity, rash, urticaria, necrotizing angiitis (vasculitis) (cutaneous vasculitis).

Cardiovascular reaction: orthostatic hypotension may occur and may be aggravated by alcohol, barbiturates, or narcotics.

Other: hyperglycemia, glycosuria, hyperuricemia, muscle spasm, weakness, restlessness.

Whenever adverse reactions are moderate or severe, thiazide dosage should be reduced or therapy withdrawn.